Hello, 英文的問句通常用單數為基準來詢問 因為在不知單數或複數得情況下 ,用單數問是最恰當的. ex: Who is in the kitchen? Mom is in the kitchen. ex: Who is in the kitchen? Mary and Tracy are in the kitchen. ex: What is there in the box? A ball is in the box. ex: What is there in the box? Some books and pens in the box. 因此用What is the difference between A and B.來詢問是對的, 即使回答時A和B有很多不同點.